Data of  Cancer Therapy Peptides


Target

>60

Cancer cell line

>400


Total

6214

Peptide Library

6106

Drug Library

108

Welcome to DCTPep

DCTPep (Data of cancer therapy peptides) is an open data repository of cancer therapy peptides, composed of two sub libraries: Peptide Library and Drug Library. It has been developed to provide the scientists with the information for designing new anticancer peptides and targeted peptide conjugated anticancer agents with a high selectivity.

Peptide Library: Tumor active peptide, Cancer targeted peptides, Targeted peptide conjugates... In addition to traditional anticancer peptides that are part of antimicrobial peptides, DCTPep also focuses on the collection of targeted peptides. These peptides can target receptors on cancer cell membranes or biomarkers related to cancer cell growth, invasion, and proliferation to exert antitumor effects.

Drug Library: Approved and clinical drug peptides for cancer treatment.

Data in the DCTPep is made available under an CCBY 4.0 License. You are entitled to access and use the services and download or extract data. The free services are offered for the purpose of providing access to summarized data, analytics, metadata, and bulk downloads.

If there are any errors in the database, please do not hesitate to contact us, please email to zhengh18@hotmail.com.

*Citation*:

Sun, X., Liu, Y., Ma, T. et al. DCTPep, the data of cancer therapy peptides. Sci Data 11, 541 (2024). DOI: 10.1038/s41597-024-03388-9 PMID: 38796630

Active mechanism of anticancer peptide

External Links

Contact: Zheng Heng, Ph.D.
zhengh18@hotmail.com

NEWS & EVENTS

  • March 12, 2023 Data reviewed!

  • September 19, 2023 Upload predicted structures 113.

  • May 17, 2023 Database updated! Updated annotation information for entries existed in DCTPep.

  • March 9, 2023 Drug library updated! Field reorganization and added structure annotations.

  • January 6, 2023 Database updated! Added 'classification' field.

  • September 23, 2022 Integrated Mol* Viewer to replace 3Dmol for web display and editing of predicted structures of anticancer peptide.

  • June 10, 2022 Added 'Link' field, including the corresponding DRAMP ID, DBAASP ID, CancerPPD ID for the peptide entry...

  • April 22, 2022 Peptide library updated!

  • October 20, 2022 Data collation. Set up two sub libraries: peptide library and drug library. Peptide libraries store anticancer active peptides, while drug libraries store anticancer drug peptides that enter clinical practice.

  • January 1, 2022 Database updated!

  • November 7, 2021 Integrated 3Dmol for web display and editing of 3D structures of anticancer peptide.

  • August 8, 2021 Added annotation information about peptide drugs, including 85 active ingredient annotation information of peptide drugs, and corresponding peptide drugs preparations.

  • May 23, 2021 Integrated BLAST Similarity search system for anticancer peptide sequence--"Similarity search".

  • March 1, 2021 DCTPep Setup! Welcome to comment and suggest!

DCTPep is developed by Dr.Zheng's team.