This work is licensed under a Creative Commons Attribution 4.0 International License.
Antifungal lectin PVAP
General Information
DCTPep ID DCTPep00143
Peptide Name Antifungal lectin PVAP
Sequence SNDIYFNFQR
Sequence Length 10
UniProt ID Not available
PubChem CID Not available
Origin Phaseolus vulgaris
Type Native peptide
Classification
ACP Tumor active peptide
Activity Information
| Cell Line | Disease | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|
| L1210 | Mouse leukemia | IC50=3.6 µM | Radioactive precursor assay | 48h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Mouse splenocytes: NA
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C59H82N16O18
Absent amino acids ACEGHKLMPTVW
Theoretical pI 5.55
Acidic residues 1
Basic residues 1
Polar residues 4
Molecular weight (Average) 1303.4
Molecular weight (Monoisotopic) 1302.6
Common amino acids FN
Net charge 0
Instability index (II) -6.03
Aliphatic index 39.00
Grand average of hydropathicity (GRAVY) -1.050
Half Life
1.9 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 1.143
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 16026901
Title An antifungal protein from flageolet beans
Doi 10.1016/j.peptides.2005.06.003
Year 2005
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.