DCTPep ID  DCTPep00212

Peptide Name   Temporin-CEa

Sequence  FVDLKKIANIINSIF

Sequence Length  15

UniProt ID  Not available

PubChem CID  Not available

Origin  skin of the Chinese brown frog, Rana chensinensis

Type  Native peptide

Hemolytic Activity  Human erythrocytes: LD50=230 μM

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

PDB ID  Not available

Predicted Structure  DCTPep00212

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L

Grand average of hydropathicity (GRAVY)  0.953

Half Life 
  1.1 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution

Literature 1

Pubmed ID 19341344

Title  Molecular cloning of cDNAs encoding antimicrobial peptide precursors from the skin of the Chinese brown frog, Rana chensinensis

Doi 10.2108/zsj.26.220

Year  2009

Literature 2

Pubmed ID 21871946

Title  Antitumor effects and cell selectivity of temporin-1CEa, an antimicrobial peptide from the skin secretions of the Chinese brown frog (Rana chensinensis)

Doi 10.1016/j.biochi.2011.08.011

Year  2012

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available