Peptide Libraray

Peptide L6D/L12D/L17D/L20D

General Information

DCTPep ID DCTPep00428

Peptide Name Peptide L6D/L12D/L17D/L20D

Sequence KWKSFlKTFKSlKKTVlHTlLKAISS

Sequence Length 26

UniProt ID Not available

PubChem CID Not available

Origin Acetylation

Type Synthetic peptide

Classification

ACP Tumor active peptide

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
HeLa	Human papillomavirus-related endocervical adenocarcinoma	IC50=9.69±0.38 µmol/L	MTS assay	1 h	1

Hemolytic Activity Human red blood cells: MHC=81.31±1.05 μmol/L

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Acetylation

C-terminal Modification Amidation

Other Modification None

Chiral Mix

Physicochemical Information

Formula Not Applicable

Absent amino acids Not Applicable

Theoretical pI Not Applicable

Acidic residues Not Applicable

Basic residues Not Applicable

Polar residues Not Applicable

Molecular weight (Average) Not Applicable

Molecular weight (Monoisotopic) Not Applicable

Common amino acids Not Applicable

Net charge Not Applicable

Instability index (II) Not Applicable

Aliphatic index Not Applicable

Grand average of hydropathicity (GRAVY) Not Applicable

Half Life
Not Applicable

Extinction coefficients
Not Applicable

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 22837667

Title Role of helicity on the anticancer mechanism of action of cationic-helical peptides

Doi 10.3390/ijms13066849

Year 2012

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available