This work is licensed under a Creative Commons Attribution 4.0 International License.
ltc2aG11A
General Information
DCTPep ID DCTPep00432
Peptide Name ltc2aG11A
Sequence GLFGKLIKKFARKAISYAVKKARGKH
Sequence Length 26
UniProt ID Not available
PubChem CID Not available
Origin Central Asian spider, Lachesana tarabaevi
Type Native peptide
Classification
ACP Tumor active peptide
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep00432
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C137H231N41O29
Absent amino acids CDEMNPQTW
Theoretical pI 11.33
Acidic residues 0
Basic residues 10
Polar residues 5
Molecular weight (Average) 2916.6
Molecular weight (Monoisotopic) 2914.79
Common amino acids K
Net charge 10
Instability index (II) 1.29
Aliphatic index 86.54
Grand average of hydropathicity (GRAVY) -0.354
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.511
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22885172
Title Imaging the membrane lytic activity of bioactive peptide latarcin 2a
Doi 10.1016/j.bbamem.2012.07.030
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.