αs1-casein f(90_95)
General Information
DCTPep ID DCTPep00452
Peptide Name αs1-casein f(90_95)
Sequence RYLGYL
Sequence Length 6
UniProt ID Not available
PubChem CID Not available
Origin Bovine milk
Type Native peptide
Classification
ACP Tumor active peptide
Activity Information
Cell Line | Disease | Activity | Assay | Testing Time | Literature |
---|---|---|---|---|---|
AZ-97 | Colon carcinoma | Inhibition at 12-15 g/l | MTT assay | Not available | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C38H57N9O9
Absent amino acids ACDEFHIKMNPQSTVW
Theoretical pI 8.59
Acidic residues 0
Basic residues 1
Polar residues 3
Molecular weight (Average) 783.93
Molecular weight (Monoisotopic) 783.43
Common amino acids LY
Net charge 1
Instability index (II) -18.38
Aliphatic index 130.00
Grand average of hydropathicity (GRAVY) 0.017
Half Life
1 hours (mammalian reticulocytes, in vitro).
2 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 2980
Abs 0.1% (=1 g/l) 3.801
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23533710
Title Potential anticarcinogenic peptides from bovine milk
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available