αs1-casein f(90_95)

General Information


DCTPep ID  DCTPep00452

Peptide Name   αs1-casein f(90_95)

Sequence  RYLGYL

Sequence Length  6

UniProt ID  Not available

PubChem CID  Not available

Origin  Bovine milk

Type  Native peptide

Classification

  

ACP Tumor active peptide



Activity Information


Cell Line Disease Activity Assay Testing Time Literature
AZ-97 Colon carcinoma Inhibition at 12-15 g/l MTT assay Not available 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C38H57N9O9

Absent amino acids  ACDEFHIKMNPQSTVW

Theoretical pI  8.59

Acidic residues  0

Basic residues  1

Polar residues  3

Molecular weight (Average)  783.93

Molecular weight (Monoisotopic)  783.43

Common amino acids  LY

Net charge  1

Instability index (II)  -18.38

Aliphatic index  130.00

Grand average of hydropathicity (GRAVY)  0.017

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  2 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 2980
  Abs 0.1% (=1 g/l) 3.801

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 23533710

Title  Potential anticarcinogenic peptides from bovine milk

Doi 10.1155/2013/939804

Year  2013

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DCTPep is developed by Dr.Zheng's team.