Peptide Libraray

Bacteriocin ASP-1

General Information

DCTPep ID DCTPep00784

Peptide Name Bacteriocin ASP-1

Sequence FTVAXFI

Sequence Length 7

UniProt ID Not available

PubChem CID Not available

Origin Bacillus subtilis URID 12.1

Type Native peptide

Classification

ACP Tumor active peptide

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
HepG2	Hepatoblastoma	IC50=192µg/ml	MTS assay	24h	1
MCF-7	Invasive breast carcinoma of no special type	IC50=280µg/ml	MTS assay	24h	1

Hemolytic Activity Human erythrocytes: <5% Hemolysis=128µg/ml; 30% Hemolysis=256µg/ml

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Cyclic

Disulfide/Other Bond LCB: X(5)<--->Ile7

N-terminal Modification Acetylation

C-terminal Modification Free

Other Modification X=dehydrobutyrine

Chiral L

Physicochemical Information

Formula Not Applicable

Absent amino acids Not Applicable

Theoretical pI Not Applicable

Acidic residues Not Applicable

Basic residues Not Applicable

Polar residues Not Applicable

Molecular weight (Average) Not Applicable

Molecular weight (Monoisotopic) Not Applicable

Common amino acids Not Applicable

Net charge Not Applicable

Instability index (II) Not Applicable

Aliphatic index Not Applicable

Grand average of hydropathicity (GRAVY) Not Applicable

Half Life
Not Applicable

Extinction coefficients
Not Applicable

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 28887200

Title Purification and characterization of a novel anti-staphylococcal peptide (ASP-1) from bacillus sp. URID 12.1

Doi 10.1016/j.ijantimicag.2017.08.030

Year 2018

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available