Peptide Libraray

LfcinB (20–25)cyc

General Information

DCTPep ID DCTPep00795

Peptide Name LfcinB (20–25)cyc

Sequence CRRWQWRXC

Sequence Length 9

UniProt ID Not available

PubChem CID Not available

Origin Bovine Lactoferricin

Type Native peptide

Classification

Cancer therapy related peptides

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
MDA-MB-231	Breast adenocarcinoma	IC50>200 μM	MTT assay	2h	1
MDA-MB-468	Breast adenocarcinoma	IC50>200 μM	MTT assay	2h	1

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Cyclic

Disulfide/Other Bond Cys1<--->Cys10

N-terminal Modification Free

C-terminal Modification Free

Other Modification X=Ahx

Chiral L

Physicochemical Information

Formula Not Applicable

Absent amino acids Not Applicable

Theoretical pI Not Applicable

Acidic residues Not Applicable

Basic residues Not Applicable

Polar residues Not Applicable

Molecular weight (Average) Not Applicable

Molecular weight (Monoisotopic) Not Applicable

Common amino acids Not Applicable

Net charge Not Applicable

Instability index (II) Not Applicable

Aliphatic index Not Applicable

Grand average of hydropathicity (GRAVY) Not Applicable

Half Life
Not Applicable

Extinction coefficients
Not Applicable

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 28961215

Title Antibacterial Synthetic Peptides Derived from Bovine Lactoferricin Exhibit Cytotoxic Effect against MDA-MB-468 and MDA-MB-231 Breast Cancer Cell Lines

Doi 10.3390/molecules22101641

Year 2017

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available