Peptide Libraray

Ovalbumin (277-287)[V5R, P8R, K11I]

General Information

DCTPep ID DCTPep01003

Peptide Name Ovalbumin (277-287)[V5R, P8R, K11I]

Sequence RKIKRYLRRMI

Sequence Length 11

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

Cancer therapy related peptides

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
HeLa	Human papillomavirus-related endocervical adenocarcinoma	10% Killing=600 µg/ml	WST-8 assay	24h	1

Hemolytic Activity Mouse erythrocytes: 10% Hemolysis=1660µg/ml

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C68H125N25O13S1

Absent amino acids ACDEFGHNPQSTVW

Theoretical pI 12.01

Acidic residues 0

Basic residues 6

Polar residues 1

Molecular weight (Average) 1532.96

Molecular weight (Monoisotopic) 1531.96

Common amino acids R

Net charge 6

Instability index (II) 86.02

Aliphatic index 106.36

Grand average of hydropathicity (GRAVY) -1.127

Half Life
1 hours (mammalian reticulocytes, in vitro).
2 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.972

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 32715598

Title Antimicrobial activity and secondary structure of a novel peptide derived from ovalbumin

Doi 10.1002/psc.3276

Year 2020

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available