DCTPep ID  DCTPep01009

Peptide Name   Ranatuerin-2SSa

Sequence  GLISTIWNTASNVAGTLTDSVKCKFKKC

Sequence Length  28

UniProt ID  Not available

PubChem CID  Not available

Origin  Glandirana susurra

Type  Native peptide

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  COS-7: 88.5% Killing=32µg/ml; CPAE: 99.2% Killing=32µg/ml

Target  Not available

Affinity  Not available

Mechanism  Not available

PDB ID  Not available

Predicted Structure  DCTPep01009

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L

Grand average of hydropathicity (GRAVY)  0.121

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 5625
  Abs 0.1% (=1 g/l) 1.883, assuming all pairs of Cys residues form cystines
  Ext. coefficient 5500
  Abs 0.1% (=1 g/l) 1.842, assuming all Cys residues are reduced

Amino acid distribution

Literature 1

Pubmed ID 32751229

Title  Antimicrobial Property and Mode of Action of the Skin Peptides of the Sado Wrinkled Frog, Glandirana susurra, against Animal and Plant Pathogens

Doi 10.3390/antibiotics9080457

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available