Peptide Libraray

HS6

General Information

DCTPep ID DCTPep01045

Peptide Name HS6

Sequence GAISLAKLQINeG

Sequence Length 13

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

ACP Tumor active peptide Cancer targeted peptides

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
CT26	Mouse colon adenocarcinoma	IC50=0.71±0.22 µM	MTT assay	24, 48, 72h	1

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target programmed cell death protein 1

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Cyclic

Disulfide/Other Bond Not available

N-terminal Modification Acetylization

C-terminal Modification Amidation

Other Modification C,N-terminal lactam peptide; e=D-Glutamic acid

Chiral Mix

Physicochemical Information

Formula Not Applicable

Absent amino acids Not Applicable

Theoretical pI Not Applicable

Acidic residues Not Applicable

Basic residues Not Applicable

Polar residues Not Applicable

Molecular weight (Average) Not Applicable

Molecular weight (Monoisotopic) Not Applicable

Common amino acids Not Applicable

Net charge Not Applicable

Instability index (II) Not Applicable

Aliphatic index Not Applicable

Grand average of hydropathicity (GRAVY) Not Applicable

Half Life
Not Applicable

Extinction coefficients
Not Applicable

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 33360579

Title Design, synthesis and evaluation of PD-L1 peptide antagonists as new anticancer agents for immunotherapy

Doi 10.1016/j.bmc.2020.115951

Year 2021

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available