This work is licensed under a Creative Commons Attribution 4.0 International License.
Temporin-G
General Information
DCTPep ID DCTPep01049
Peptide Name Temporin-G
Sequence FFPVIGRILNGIL
Sequence Length 13
UniProt ID Not available
PubChem CID Not available
Origin Rana temporaria
Type Native peptide
Classification
ACP Tumor active peptide
Activity Information
| Cell Line | Disease | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|
| A549 | Lung adenocarcinoma | 50% Cytotoxicity=73µM | MTT assay | 24h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep01049
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C72H115N17O15
Absent amino acids ACDEHKMQSTWY
Theoretical pI 9.75
Acidic residues 0
Basic residues 1
Polar residues 3
Molecular weight (Average) 1458.81
Molecular weight (Monoisotopic) 1457.88
Common amino acids I
Net charge 1
Instability index (II) 50.4
Aliphatic index 172.31
Grand average of hydropathicity (GRAVY) 1.577
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33538061
Title Temporin G, an amphibian antimicrobial peptide against influenza and parainfluenza respiratory viruses: Insights into biological activity and mechanism of action
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.