YALPAR

General Information


DCTPep ID  DCTPep01119

Peptide Name   YALPAR

Sequence  YALPAR

Sequence Length  6

UniProt ID  Not available

PubChem CID  Not available

Origin  Heated products of peptic hydrolysates of half-fin anchovy (Setipinna taty)

Type  Native peptide

Classification

  

ACP Tumor active peptide



Activity Information


Cell Line Disease Activity Assay Testing Time Literature
PC-3 Prostate carcinoma IC50=19.0 μM (13.1 mg/mL) MTT assay 48h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C32H51N9O8

Absent amino acids  CDEFGHIKMNQSTVW

Theoretical pI  8.75

Acidic residues  0

Basic residues  1

Polar residues  1

Molecular weight (Average)  689.81

Molecular weight (Monoisotopic)  689.39

Common amino acids  A

Net charge  1

Instability index (II)  112

Aliphatic index  98.33

Grand average of hydropathicity (GRAVY)  0.000

Half Life 
  2.8 hours (mammalian reticulocytes, in vitro).
  10 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 2.160

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Isolation and identification of an antiproliferative peptide derived from heated products of peptic hydrolysates of half-fin anchovy (Setipinna taty)

Doi 10.1016/j.jff.2014.06.010

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DCTPep is developed by Dr.Zheng's team.