Peptide Libraray

YALRAH

General Information

DCTPep ID DCTPep01120

Peptide Name YALRAH

Sequence YALRAH

Sequence Length 6

UniProt ID Not available

PubChem CID Not available

Origin Heated products of peptic hydrolysates of half-fin anchovy (Setipinna taty)

Type Native peptide

Classification

ACP Tumor active peptide

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
PC-3	Prostate carcinoma	IC50=11.1 μM (8.1 mg/mL)	MTT assay	48h	1

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C33H51N11O8

Absent amino acids CDEFGIKMNPQSTVW

Theoretical pI 8.75

Acidic residues 0

Basic residues 2

Polar residues 1

Molecular weight (Average) 729.84

Molecular weight (Monoisotopic) 729.39

Common amino acids A

Net charge 2

Instability index (II) 65.75

Aliphatic index 98.33

Grand average of hydropathicity (GRAVY) -0.267

Half Life
2.8 hours (mammalian reticulocytes, in vitro).
10 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 2.042

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Isolation and identification of an antiproliferative peptide derived from heated products of peptic hydrolysates of half-fin anchovy (Setipinna taty)

Doi 10.1016/j.jff.2014.06.010

Year 2014

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available