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YALPAH
General Information
DCTPep ID DCTPep01124
Peptide Name YALPAH
Sequence YALPAH
Sequence Length 6
UniProt ID Not available
PubChem CID Not available
Origin Yellow crucian carp protein
Type Native peptide
Classification
ACP Tumor active peptide
Activity Information
| Cell Line | Disease | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|
| PC-3 | Prostate carcinoma | IC50=6.32 μM/mL | MTT assay | Not available | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Inhibit cell proliferation and inducing apoptosis
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C32H46N8O8
Absent amino acids CDEFGIKMNQRSTVW
Theoretical pI 6.74
Acidic residues 0
Basic residues 1
Polar residues 1
Molecular weight (Average) 670.77
Molecular weight (Monoisotopic) 670.34
Common amino acids A
Net charge 1
Instability index (II) 97.85
Aliphatic index 98.33
Grand average of hydropathicity (GRAVY) 0.217
Half Life
2.8 hours (mammalian reticulocytes, in vitro).
10 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 2.221
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN103665103B
Patent Title Method for separating out prostatic cancer (PC)-3 anticancer peptide by utilizing thermal reactant of setipinna taty antibacterial peptide liquid and anticancer peptide obtained by using method
Other Iinformation Granted Patent; Family: 2s / 2ex; Family Jurisdictions: CN; Legal Status: Active; Application No: 201310460838; Filed: Sep 29, 2013; Published: Apr 6, 2016; Earliest Priority: Sep 29, 2013; Granted: Apr 6, 2016
Other Published ID CN103665103B
This work is licensed under a Creative Commons Attribution 4.0 International License.