This work is licensed under a Creative Commons Attribution 4.0 International License.
OPB
General Information
DCTPep ID DCTPep01125
Peptide Name OPB
Sequence GNKKWEQKQVQIKTLEGEFSVTMWSS
Sequence Length 26
PubChem CID Not available
Origin YY1 protein
Type Native peptide
Classification
ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Is nontoxic to normal breast cell
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep01125
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C137H214N36O42S1
Absent amino acids ACDHPRY
Theoretical pI 8.43
Acidic residues 3
Basic residues 4
Polar residues 8
Molecular weight (Average) 3069.48
Molecular weight (Monoisotopic) 3067.54
Common amino acids K
Net charge 1
Instability index (II) 27.05
Aliphatic index 52.31
Grand average of hydropathicity (GRAVY) -0.965
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 3.584
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN105601724B
Patent Title Anticancer active OPB (oligopeptidase B) oligopeptide and expression vector and application thereof
Other Iinformation Granted Patent; Family: 2s / 2ex; Family Jurisdictions: CN; Legal Status: Active; Application No: 201610018929 Filed: Jan 12, 2016 Published: Jun 7, 2019 Earliest Priority: Jan 12, 2016; Granted: Jun 7, 2019
Other Published ID CN105601724B
This work is licensed under a Creative Commons Attribution 4.0 International License.