Peptide Libraray

SEQ ID NO: 2 from EP2716297B1

General Information

DCTPep ID DCTPep01158

Peptide Name SEQ ID NO: 2 from EP2716297B1

Sequence LNQEDARKSE

Sequence Length 10

UniProt ID Not available

PubChem CID Not available

Origin Screen of phage display peptide library

Type Native peptide

Classification

ACP

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C47H80N16O20

Absent amino acids CFGHIMPTVWY

Theoretical pI 4.68

Acidic residues 3

Basic residues 2

Polar residues 2

Molecular weight (Average) 1189.25

Molecular weight (Monoisotopic) 1188.57

Common amino acids E

Net charge -1

Instability index (II) 59.24

Aliphatic index 49.00

Grand average of hydropathicity (GRAVY) -2.110

Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).

Extinction coefficients
Should not be visible by UV spectrophotometry.

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID EP2524926B1

Patent Title Anticancer Peptide Sequence

Other Iinformation Granted Patent; Family: 7s / 7ex; Family Jurisdictions: EP, KR, WO; Legal Status: Active; Application No: 10843287; Filed: Dec 27, 2010; Published: Mar 9, 2016; Earliest Priority: Jan 12, 2010; Granted: Mar 9, 2016

Other Published ID EP2524926A4 EP2524926B1 KR101815322B1 KR20110082954A WO2011087222A2 WO2011087222A3