This work is licensed under a Creative Commons Attribution 4.0 International License.
Ⅰ
General Information
DCTPep ID DCTPep01179
Peptide Name Ⅰ
Sequence XPAXXFXPAXXLXXLXXLX
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Peptaibols
Type Native peptide
Classification
ACP Tumor active peptide
Activity Information
| Cell Line | Disease | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|
| BEL-7402 | Human papillomavirus-related endocervical adenocarcinoma | IC50=1.98 μM | MTT assay | 3-5 days | Patent |
| BGC-823 | Human papillomavirus-related endocervical adenocarcinoma | IC50=2.11 μM | MTT assay | 3-5 days | Patent |
| A549 | Lung adenocarcinoma | IC50=2.30 μM | MTT assay | 3-5 days | Patent |
| A2780 | Ovarian endometrioid adenocarcinoma; Endometrioid carcinoma of ovary | IC50>10 μM | MTT assay | 3-5 days | Patent |
| HCT 8 | Colon adenocarcinoma | IC50>10 μM | MTT assay | 3-5 days | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Aminoethanol
Other Modification X(1/4/5/16/17)=Aib=1-amino-isobutyric acid; X(7/13)=Iva=Isovaline; X(10)=AHMA=3-amino-2-hydroxy-3-methylbutanoic acid; X(11/14/19)(β)A=β-Alanine
Chiral L
Physicochemical Information
Formula Not Applicable
Absent amino acids Not Applicable
Theoretical pI Not Applicable
Acidic residues Not Applicable
Basic residues Not Applicable
Polar residues Not Applicable
Molecular weight (Average) Not Applicable
Molecular weight (Monoisotopic) Not Applicable
Common amino acids Not Applicable
Net charge Not Applicable
Instability index (II) Not Applicable
Aliphatic index Not Applicable
Grand average of hydropathicity (GRAVY) Not Applicable
Half Life
Not Applicable
Extinction coefficients
Not Applicable
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.