Peptide Libraray

VP22, Sequence 12 from Patent US 20030077289

General Information

DCTPep ID DCTPep01232

Peptide Name VP22, Sequence 12 from Patent US 20030077289

Sequence DAATATRGRSAASRPTERPRAPARSASRPRRPVE

Sequence Length 34

UniProt ID Not available

PubChem CID Not available

Origin Herpes simplex virus 1

Type Native peptide

Classification

ACP

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure DCTPep01232

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Not available

Disulfide/Other Bond Not available

N-terminal Modification Not available

C-terminal Modification Not available

Other Modification None

Chiral L

Physicochemical Information

Formula C148H257N61O48

Absent amino acids CFHIKLMNQWY

Theoretical pI 12.10

Acidic residues 3

Basic residues 9

Polar residues 8

Molecular weight (Average) 3659.05

Molecular weight (Monoisotopic) 3656.95

Common amino acids R

Net charge 6

Instability index (II) 102.11

Aliphatic index 32.06

Grand average of hydropathicity (GRAVY) -1.356

Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).

Extinction coefficients
Should not be visible by UV spectrophotometry.

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID US 2003/0077289 A1

Patent Title Use of cell-penetrating peptides to generate antitumor immunity.

Other Iinformation Granted Patent Family: 6s / 6ex; Family Jurisdictions: CN, WO, AU, US; Legal Status: Discontinued; Application No: 7755502; Filed:Feb 15, 2002; Published: Apr 24, 2003; Earliest Priority: Feb 15, 2001

Other Published ID CN1309417C CN1503628A WO2002064057A2 WO2002064057A3