Sequence 10 from Patent US 20040043936
General Information
DCTPep ID DCTPep01251
Peptide Name Sequence 10 from Patent US 20040043936
Sequence CVHTYRA
Sequence Length 7
UniProt ID Not available
PubChem CID Not available
Origin Sos scrofus (Pig)
Type Native peptide
Classification
ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C36H56N12O10S1
Absent amino acids DEFGIKLMNPQSW
Theoretical pI 8.23
Acidic residues 0
Basic residues 2
Polar residues 3
Molecular weight (Average) 848.98
Molecular weight (Monoisotopic) 848.4
Common amino acids ACHRTVY
Net charge 2
Instability index (II) -37.13
Aliphatic index 55.71
Grand average of hydropathicity (GRAVY) -0.171
Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 1.755, assuming all pairs of Cys residues form cystines
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 1.755, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2004/0043936 A1
Patent Title Antiproliferative and antiviral proteins and peptides.
Other Iinformation Granted Patent Family: 11s / 14ex; Family Jurisdictions: EP, IL, AU, US, AT, DE; Legal Status: Expired; Application No: 67049003; Filed:Sep 25, 2003; Published: Mar 4, 2004; Earliest Priority: Jul 2, 1998; Granted: Jan 13, 2009
Other Published ID DE69937998D1 DE69937998T2 EP1091753A1 EP1091753A4 EP1091753B1 US7476649