Sequence 9 from Patent US 20040043936

General Information


DCTPep ID  DCTPep01252

Peptide Name   Sequence 9 from Patent US 20040043936

Sequence  CVHTYRS

Sequence Length  7

UniProt ID  Not available

PubChem CID  Not available

Origin  Sos scrofus (Pig)

Type  Native peptide

Classification

  

ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Not available

C-terminal Modification  Not available

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C36H56N12O11S1

Absent amino acids  ADEFGIKLMNPQW

Theoretical pI  8.23

Acidic residues  0

Basic residues  2

Polar residues  4

Molecular weight (Average)  864.97

Molecular weight (Monoisotopic)  864.39

Common amino acids  CHRSTVY

Net charge  2

Instability index (II)  25.64

Aliphatic index  41.43

Grand average of hydropathicity (GRAVY)  -0.543

Half Life 
  1.2 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 1.723, assuming all pairs of Cys residues form cystines
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 1.723, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2004/0043936 A1

Patent Title  Antiproliferative and antiviral proteins and peptides.

Other Iinformation  Granted Patent Family: 11s / 14ex; Family Jurisdictions: EP, IL, AU, US, AT, DE; Legal Status: Expired; Application No: 67049003; Filed:Sep 25, 2003; Published: Mar 4, 2004; Earliest Priority: Jul 2, 1998; Granted: Jan 13, 2009

Other Published ID  DE69937998D1  DE69937998T2  EP1091753A1  EP1091753A4  EP1091753B1  US7476649 




DCTPep is developed by Dr.Zheng's team.