Sequence 3 from Patent US 20050239703
General Information
DCTPep ID DCTPep01253
Peptide Name Sequence 3 from Patent US 20050239703
Sequence ELKCYTCKEPMTSAACRTIT
Sequence Length 20
UniProt ID Not available
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep01253
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C93H157N25O31S4
Absent amino acids DFGHNQVW
Theoretical pI 8.03
Acidic residues 2
Basic residues 3
Polar residues 9
Molecular weight (Average) 2249.66
Molecular weight (Monoisotopic) 2248.04
Common amino acids T
Net charge 1
Instability index (II) 27.4
Aliphatic index 49.00
Grand average of hydropathicity (GRAVY) -0.225
Half Life
1 hours (mammalian reticulocytes, in vitro).
30 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1615
Abs 0.1% (=1 g/l) 0.718, assuming all pairs of Cys residues form cystines
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.662, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2005/0239703 A1
Patent Title Anticancer peptide compositions.
Other Iinformation Granted Patent Family: 3s / 3ex; Family Jurisdictions: US, WO; Legal Status: Inactive; Application No: 97762904; Filed:Oct 29, 2004; Published: Oct 27, 2005; Earliest Priority: Oct 29, 2003; Granted: Feb 5, 2008
Other Published ID US7326679 WO2005042001A1