Sequence 1 from Patent US 20050239703

General Information


DCTPep ID  DCTPep01254

Peptide Name   Sequence 1 from Patent US 20050239703

Sequence  ELKCYTCKEPMTSASCRTIT

Sequence Length  20

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic construct

Type  Synthetic peptide

Classification

  

ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  DCTPep01254

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Not available

C-terminal Modification  Not available

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C93H157N25O32S4

Absent amino acids  DFGHNQVW

Theoretical pI  8.03

Acidic residues  2

Basic residues  3

Polar residues  10

Molecular weight (Average)  2265.66

Molecular weight (Monoisotopic)  2264.03

Common amino acids  T

Net charge  1

Instability index (II)  21.73

Aliphatic index  44.00

Grand average of hydropathicity (GRAVY)  -0.355

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  30 min (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 1615
  Abs 0.1% (=1 g/l) 0.713, assuming all pairs of Cys residues form cystines
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 0.658, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2005/0239703 A1

Patent Title  Anticancer peptide compositions.

Other Iinformation  Granted Patent Family: 3s / 3ex; Family Jurisdictions: US, WO; Legal Status: Inactive; Application No: 97762904; Filed:Oct 29, 2004; Published: Oct 27, 2005; Earliest Priority: Oct 29, 2003; Granted: Feb 5, 2008

Other Published ID  US7326679  WO2005042001A1 




DCTPep is developed by Dr.Zheng's team.