Peptide Libraray

Sequence 11 from Patent US 20070293424

General Information

DCTPep ID DCTPep01299

Peptide Name Sequence 11 from Patent US 20070293424

Sequence HGGGWGQGGGTHS

Sequence Length 13

UniProt ID Q9Z0T3 P40256 P61766 P40257 P04156 P40251 P40252 P40247

PubChem CID Not available

Origin Homo sapiens

Type Native peptide

Classification

ACP

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure DCTPep01299

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Not available

Disulfide/Other Bond Not available

N-terminal Modification Not available

C-terminal Modification Not available

Other Modification None

Chiral L

Physicochemical Information

Formula C49H67N19O17

Absent amino acids ACDEFIKLMNPRVY

Theoretical pI 6.92

Acidic residues 0

Basic residues 2

Polar residues 9

Molecular weight (Average) 1194.19

Molecular weight (Monoisotopic) 1193.5

Common amino acids G

Net charge 2

Instability index (II) 34.21

Aliphatic index 0.00

Grand average of hydropathicity (GRAVY) -1.162

Half Life
3.5 hours (mammalian reticulocytes, in vitro).
10 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 4.606

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID US 2007/0293424 A1

Patent Title Antitumoral and Antiviral Peptides.

Other Iinformation Granted Patent Family: 10s / 10ex; Family Jurisdictions: EP, RU, AU, ZA, US, WO; Legal Status: Active; Application No: 58571504 ; Filed:Dec 30, 2004; Published: Dec 20, 2007; Earliest Priority: Jan 15, 2004; Granted: Feb 12, 2013

Other Published ID EP1705182A1 EP1705182A4 EP1705182B1 US8372406 WO2005068491A1