Sequence 1 from Patent US 20070293424
General Information
DCTPep ID DCTPep01302
Peptide Name Sequence 1 from Patent US 20070293424
Sequence HGVSGWGQHGTHG
Sequence Length 13
UniProt ID Not available
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep01302
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C56H77N21O17
Absent amino acids ACDEFIKLMNPRY
Theoretical pI 7.02
Acidic residues 0
Basic residues 3
Polar residues 7
Molecular weight (Average) 1316.36
Molecular weight (Monoisotopic) 1315.58
Common amino acids G
Net charge 3
Instability index (II) -19.72
Aliphatic index 22.31
Grand average of hydropathicity (GRAVY) -1.023
Half Life
3.5 hours (mammalian reticulocytes, in vitro).
10 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 4.178
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2007/0293424 A1
Patent Title Antitumoral and Antiviral Peptides.
Other Iinformation Granted Patent Family: 10s / 10ex; Family Jurisdictions: EP, RU, AU, ZA, US, WO; Legal Status: Active; Application No: 58571504 ; Filed:Dec 30, 2004; Published: Dec 20, 2007; Earliest Priority: Jan 15, 2004; Granted: Feb 12, 2013
Other Published ID EP1705182A1 EP1705182A4 EP1705182B1 US8372406 WO2005068491A1