Sequence 17 from Patent US 20110159022

General Information


DCTPep ID  DCTPep01325

Peptide Name   Sequence 17 from Patent US 20110159022

Sequence  AQTQRIRCRV

Sequence Length  10

UniProt ID  P21741  A5DCV3  B5Z8L0  Q1CS51  O25812  Q9ZK11  Q17VM4 

PubChem CID  Not available

Origin  Synthetic construct

Type  Synthetic peptide

Classification

  

ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Not available

C-terminal Modification  Not available

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C49H91N21O14S1

Absent amino acids  DEFGHKLMNPSWY

Theoretical pI  11.70

Acidic residues  0

Basic residues  3

Polar residues  2

Molecular weight (Average)  1230.45

Molecular weight (Monoisotopic)  1229.68

Common amino acids  R

Net charge  3

Instability index (II)  1.46

Aliphatic index  78.00

Grand average of hydropathicity (GRAVY)  -0.820

Half Life 
  4.4 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all pairs of Cys residues form cystines
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2011/0159022 A1

Patent Title  Immunogenic Peptides Derived from the Midkine Protein, as an Anticancer Vaccine.

Other Iinformation  Granted Patent Family: 9s / 9ex; Family Jurisdictions: EP, US, JP, CN, CA, AU, WO, FR; Legal Status: Discontinued; Application No: 200913000302; Filed:Jun 20, 2009; Published: Jun 30, 2011; Earliest Priority: Jun 20, 2008;

Other Published ID  CA2728459A1  CN102123731A  EP2296697A1  WO2009153463A1 




DCTPep is developed by Dr.Zheng's team.