Sequence 37 from Patent US 20110159022
General Information
DCTPep ID DCTPep01333
Peptide Name Sequence 37 from Patent US 20110159022
Sequence EKKYFAATQFEPLAARL
Sequence Length 17
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep01333
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C93H143N23O25
Absent amino acids CDGHIMNSVW
Theoretical pI 8.59
Acidic residues 2
Basic residues 3
Polar residues 2
Molecular weight (Average) 1983.3
Molecular weight (Monoisotopic) 1982.06
Common amino acids A
Net charge 1
Instability index (II) 11.87
Aliphatic index 69.41
Grand average of hydropathicity (GRAVY) -0.353
Half Life
1 hours (mammalian reticulocytes, in vitro).
30 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.751
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2011/0159022 A1
Patent Title Immunogenic Peptides Derived from the Midkine Protein, as an Anticancer Vaccine.
Other Iinformation Granted Patent Family: 9s / 9ex; Family Jurisdictions: EP, US, JP, CN, CA, AU, WO, FR; Legal Status: Discontinued; Application No: 200913000302; Filed:Jun 20, 2009; Published: Jun 30, 2011; Earliest Priority: Jun 20, 2008;
Other Published ID CA2728459A1 CN102123731A EP2296697A1 WO2009153463A1