Peptide Libraray

Sequence 28 from Patent US 20110159022

General Information

DCTPep ID DCTPep01338

Peptide Name Sequence 28 from Patent US 20110159022

Sequence GTKVRQGTLKKARYN

Sequence Length 15

UniProt ID P21741

PubChem CID Not available

Origin Synthetic construct

Type Synthetic peptide

Classification

ACP

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure DCTPep01338

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Not available

Disulfide/Other Bond Not available

N-terminal Modification Not available

C-terminal Modification Not available

Other Modification None

Chiral L

Physicochemical Information

Formula C74H130N26O21

Absent amino acids CDEFHIMPSW

Theoretical pI 11.17

Acidic residues 0

Basic residues 5

Polar residues 6

Molecular weight (Average) 1720.01

Molecular weight (Monoisotopic) 1718.99

Common amino acids K

Net charge 5

Instability index (II) -5.49

Aliphatic index 52.00

Grand average of hydropathicity (GRAVY) -1.427

Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.866

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID US 2011/0159022 A1

Patent Title Immunogenic Peptides Derived from the Midkine Protein, as an Anticancer Vaccine.

Other Iinformation Granted Patent Family: 9s / 9ex; Family Jurisdictions: EP, US, JP, CN, CA, AU, WO, FR; Legal Status: Discontinued; Application No: 200913000302; Filed:Jun 20, 2009; Published: Jun 30, 2011; Earliest Priority: Jun 20, 2008;

Other Published ID CA2728459A1 CN102123731A EP2296697A1 WO2009153463A1