Sequence 34 from Patent US 20110159022

General Information


DCTPep ID  DCTPep01355

Peptide Name   Sequence 34 from Patent US 20110159022

Sequence  TERVRLVTRHIYNREE

Sequence Length  16

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic construct

Type  Synthetic peptide

Classification

  

ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  DCTPep01355

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Not available

C-terminal Modification  Not available

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C88H147N31O27

Absent amino acids  ACDFGKMPQSW

Theoretical pI  8.43

Acidic residues  3

Basic residues  5

Polar residues  4

Molecular weight (Average)  2071.33

Molecular weight (Monoisotopic)  2070.11

Common amino acids  R

Net charge  2

Instability index (II)  75.98

Aliphatic index  85.00

Grand average of hydropathicity (GRAVY)  -1.325

Half Life 
  7.2 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 0.719

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2011/0159022 A1

Patent Title  Immunogenic Peptides Derived from the Midkine Protein, as an Anticancer Vaccine.

Other Iinformation  Granted Patent Family: 9s / 9ex; Family Jurisdictions: EP, US, JP, CN, CA, AU, WO, FR; Legal Status: Discontinued; Application No: 200913000302; Filed:Jun 20, 2009; Published: Jun 30, 2011; Earliest Priority: Jun 20, 2008;

Other Published ID  CA2728459A1  CN102123731A  EP2296697A1  WO2009153463A1 




DCTPep is developed by Dr.Zheng's team.