This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 36 from Patent US 20110319336
General Information
DCTPep ID DCTPep01358
Peptide Name Sequence 36 from Patent US 20110319336
Sequence ATWLPPR
Sequence Length 7
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C40H61N11O9
Absent amino acids CDEFGHIKMNQSVY
Theoretical pI 9.79
Acidic residues 0
Basic residues 1
Polar residues 1
Molecular weight (Average) 839.99
Molecular weight (Monoisotopic) 839.47
Common amino acids P
Net charge 1
Instability index (II) 48.99
Aliphatic index 70.00
Grand average of hydropathicity (GRAVY) -0.529
Half Life
4.4 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 6.548
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2011/0319336 A1
Patent Title Selective anticancer chimeric peptide.
Other Iinformation Granted Patent Family: 19s / 19ex; Family Jurisdictions: US, JP, EP, WO, CN; Legal Status: Active; Application No: 200913132580; Filed: Dec 3, 2009; Published: Dec 29, 2011; Earliest Priority: Dec 3, 2008; Granted: May 7, 2013
Other Published ID CN102238965A EP2370107A2 WO2010064207A2 WO2010064207A3
This work is licensed under a Creative Commons Attribution 4.0 International License.