Sequence 11 from Patent US 20120302729
General Information
DCTPep ID DCTPep01410
Peptide Name Sequence 11 from Patent US 20120302729
Sequence DLFGRAP
Sequence Length 7
UniProt ID Q5R511 O35501 Q3ZCH0 P38647 P48721 P38646 Q5ZM98 P86233 Q57506 J7QLC0
PubChem CID Not available
Origin Synthetic construct
Type Synthetic peptide
Classification
ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C35H54N10O10
Absent amino acids CEHIKMNQSTVWY
Theoretical pI 5.84
Acidic residues 1
Basic residues 1
Polar residues 1
Molecular weight (Average) 774.87
Molecular weight (Monoisotopic) 774.4
Common amino acids ADFGLPR
Net charge 0
Instability index (II) 36.09
Aliphatic index 70.00
Grand average of hydropathicity (GRAVY) -0.229
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2012/0302729 A1
Patent Title Anticancer anti-mortalin peptide antibody.
Other Iinformation Granted Patent Family: 8s / 8ex; Family Jurisdictions: EP, US, WO, JP; Legal Status: Inactive; Application No: 201013514755; Filed:Dec 9, 2010; Published: Nov 29, 2012; Earliest Priority: Dec 10, 2009; Granted: Nov 19, 2013
Other Published ID EP2511371A1 EP2511371A4