Peptide Libraray

Sequence 24 from Patent US 20200079827

General Information

DCTPep ID DCTPep01493

Peptide Name Sequence 24 from Patent US 20200079827

Sequence GVKKKWKKKLGLKLWLKISGVVLG

Sequence Length 24

UniProt ID Not available

PubChem CID Not available

Origin Synthetic construct

Type Synthetic peptide

Classification

ACP

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure DCTPep01493

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Not available

Disulfide/Other Bond Not available

N-terminal Modification Not available

C-terminal Modification Not available

Other Modification None

Chiral L

Physicochemical Information

Formula C132H228N34O26

Absent amino acids ACDEFHMNPQRTY

Theoretical pI 10.85

Acidic residues 0

Basic residues 8

Polar residues 5

Molecular weight (Average) 2707.47

Molecular weight (Monoisotopic) 2705.76

Common amino acids K

Net charge 8

Instability index (II) 5.7

Aliphatic index 133.75

Grand average of hydropathicity (GRAVY) 0.029

Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 4.063

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID US 2020/0079827 A1

Patent Title Novel Antimicrobial And Anti-cancer Therapy

Other Iinformation Granted Patent Family: 6s / 6ex; Family Jurisdictions: EP, IL, AU, US, AT, DEUS, EP, CN, WO; Legal Status: Active; Application No: 201716462586; Filed:Nov 21, 2017; Published: Mar 12, 2020; Earliest Priority: Nov 21, 2016; Granted: Mar 29, 2022

Other Published ID WO2018094403A1 CN109996554A EP3541405A1 EP3541405A4