Peptide Libraray

Sequence 1 from Patent US 4529594

General Information

DCTPep ID DCTPep01539

Peptide Name Sequence 1 from Patent US 4529594

Sequence SASRALSDKPLAHVVANPQVEGQLQWL

Sequence Length 27

UniProt ID P04924

PubChem CID Not available

Origin Synthetic construct

Type Native peptide

Classification

ACP

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure DCTPep01539

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Not available

Disulfide/Other Bond Not available

N-terminal Modification Not available

C-terminal Modification Not available

Other Modification None

Chiral L

Physicochemical Information

Formula C129H208N38O39

Absent amino acids CFIMTY

Theoretical pI 6.47

Acidic residues 2

Basic residues 3

Polar residues 5

Molecular weight (Average) 2915.3

Molecular weight (Monoisotopic) 2913.55

Common amino acids AL

Net charge 1

Instability index (II) 27.6

Aliphatic index 104.81

Grand average of hydropathicity (GRAVY) -0.167

Half Life
1.9 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 1.887

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID US 4529594 A

Patent Title Protein having antitumor activity.

Other Iinformation Granted Patent Family: 8s / 8ex; Family Jurisdictions: EP, JP, US, DE; Legal Status: Expired; Application No: 62985384; Filed: Jul 11, 1984; Published: Jul 16, 1985; Earliest Priority: Jul 15, 1983; Granted: Jul 16, 1985

Other Published ID DE3462506D1 EP0132125A2 EP0132125A3 EP0132125B1 EP0132125B2