This work is licensed under a Creative Commons Attribution 4.0 International License.
PA-DL6K6-24
General Information
DCTPep ID DCTPep01757
Peptide Name PA-DL6K6-24
Sequence lKKllKKllKKl
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
ACP Tumor active peptide
Activity Information
| Cell Line | Disease | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|
| 22Rv1 | Prostate carcinoma | LC50<3.125 µM | MTT assay | Not available | Patent |
| CL1 | Prostate carcinoma | LC50=3.125 µM | MTT assay | Not available | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity NIH 3T3: LC50=50 μM
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification CH3(CH2)14CO, Palmitic acid
C-terminal Modification Amidation
Other Modification l=D-Leucine
Chiral Mix
Physicochemical Information
Formula Not Applicable
Absent amino acids Not Applicable
Theoretical pI Not Applicable
Acidic residues Not Applicable
Basic residues Not Applicable
Polar residues Not Applicable
Molecular weight (Average) Not Applicable
Molecular weight (Monoisotopic) Not Applicable
Common amino acids Not Applicable
Net charge Not Applicable
Instability index (II) Not Applicable
Aliphatic index Not Applicable
Grand average of hydropathicity (GRAVY) Not Applicable
Half Life
Not Applicable
Extinction coefficients
Not Applicable
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US2007/0072808A1
Patent Title Antimicrobial and anticancer lipopeptides
Other Iinformation Patent Application; Family: 11s / 13ex; Family Jurisdictions: EP, US, AU, WO, CA; Legal Status: Active; Application No: 56072704; Filed: Jun 18, 2004; Published: Mar 29, 2007; Earliest Priority: Jun 19, 2003; Granted: Mar 2, 2010
Other Published ID AU2004246909A1 AU2004246909B2 CA2529125A1 EP1633380A2 EP1633380A4 US2010160213A1 US7671011B2 US8445636B2 WO2004110341A2 WO2004110341A3
This work is licensed under a Creative Commons Attribution 4.0 International License.