PA-DL6K6-24

General Information


DCTPep ID  DCTPep01757

Peptide Name   PA-DL6K6-24

Sequence  lKKllKKllKKl

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

ACP Tumor active peptide



Activity Information


Cell Line Disease Activity Assay Testing Time Literature
22Rv1 Prostate carcinoma LC50<3.125 µM MTT assay Not available Patent
CL1 Prostate carcinoma LC50=3.125 µM MTT assay Not available Patent

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  NIH 3T3: LC50=50 μM

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  CH3(CH2)14CO, Palmitic acid

C-terminal Modification  Amidation

Other Modification  l=D-Leucine

Chiral  Mix



Physicochemical Information


Formula  Not Applicable

Absent amino acids  Not Applicable

Theoretical pI  Not Applicable

Acidic residues  Not Applicable

Basic residues  Not Applicable

Polar residues  Not Applicable

Molecular weight (Average)  Not Applicable

Molecular weight (Monoisotopic)  Not Applicable

Common amino acids  Not Applicable

Net charge  Not Applicable

Instability index (II)  Not Applicable

Aliphatic index  Not Applicable

Grand average of hydropathicity (GRAVY)  Not Applicable

Half Life 
  Not Applicable

Extinction coefficients 
  Not Applicable

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US2007/0072808A1

Patent Title  Antimicrobial and anticancer lipopeptides

Other Iinformation  Patent Application; Family: 11s / 13ex; Family Jurisdictions: EP, US, AU, WO, CA; Legal Status: Active; Application No: 56072704; Filed: Jun 18, 2004; Published: Mar 29, 2007; Earliest Priority: Jun 19, 2003; Granted: Mar 2, 2010

Other Published ID  AU2004246909A1  AU2004246909B2  CA2529125A1  EP1633380A2  EP1633380A4  US2010160213A1  US7671011B2  US8445636B2  WO2004110341A2  WO2004110341A3 




DCTPep is developed by Dr.Zheng's team.