AQTGTGKT

General Information


DCTPep ID  DCTPep01761

Peptide Name   AQTGTGKT

Sequence  AQTGTGKT

Sequence Length  8

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetics

Type  Synthetic peptide

Classification

  

ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  CAGE protein



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C30H54N10O13

Absent amino acids  CDEFHILMNPRSVWY

Theoretical pI  8.80

Acidic residues  0

Basic residues  1

Polar residues  5

Molecular weight (Average)  762.82

Molecular weight (Monoisotopic)  762.39

Common amino acids  T

Net charge  1

Instability index (II)  -33.7

Aliphatic index  12.50

Grand average of hydropathicity (GRAVY)  -1.062

Half Life 
  4.4 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US2018/0057532A1

Patent Title  Peptide Having Eight Amino Acid Sequences Derived From Cage and Retaining Anticancer Activity and Activity to Promote Anticancer Drug Sensitivity of Anticancer Drug-Resistant Cancer Cells

Other Iinformation  Patent Application; Family: 5s / 5ex; Family Jurisdictions: US, WO; Legal Status: Active; Application No: 201715624906; Filed: Jun 16, 2017; Published: Mar 1, 2018; Earliest Priority: Dec 18, 2014; Granted: Mar 26, 2019

Other Published ID  US10233221B2  US10239924B2  US2018079792A1  WO2016099188A1 




DCTPep is developed by Dr.Zheng's team.