Peptide Libraray

IDP-NS10

General Information

DCTPep ID DCTPep01770

Peptide Name IDP-NS10

Sequence AAXVVILKKXTEYVHS

Sequence Length 16

UniProt ID Not available

PubChem CID Not available

Origin Synthetics

Type Synthetic peptide

Classification

ACP Tumor active peptide

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
12O15, epithelial (glioblastoma, GMB), from surgical specimens from patients	Glioblastoma	EC50≈10 μM	CYTELL assay	72-96 h	Patent
12O53, epithelial (glioblastoma, GMB), from surgical specimens from patients	Glioblastoma	EC50≈4 μM	CYTELL assay	72-96 h	Patent
12O89, epithelial (glioblastoma, GMB), from surgical specimens from patients	Glioblastoma	EC50≈5 μM	CYTELL assay	72-96 h	Patent
RG6, epithelial (glioblastoma, GMB), from surgical specimens from patients	Glioblastoma	EC50≈5 μM	CYTELL assay	72-96 h	Patent
RG5, epithelial (glioblastoma, GMB), from surgical specimens from patients	Glioblastoma	EC50≈50 μM	CYTELL assay	72-96 h	Patent
RG1, epithelial (glioblastoma, GMB), from surgical specimens from patients	Glioblastoma	EC50≈7 μM	CYTELL assay	72-96 h	Patent
RG4, epithelial (glioblastoma, GMB), from surgical specimens from patients	Glioblastoma	EC50≈7 μM	CYTELL assay	72-96 h	Patent
GMB-27, epithelial (glioblastoma, GMB), from surgical specimens from patients	Glioblastoma	EC50≈7.5 μM	CYTELL assay	72-96 h	Patent

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification X=—(CH2)6—CH═CH—(CH2)3— (for the cases NS10, NS16 and Na05) links both Xs radicals in each sequence

Chiral L

Physicochemical Information

Formula Not Applicable

Absent amino acids Not Applicable

Theoretical pI Not Applicable

Acidic residues Not Applicable

Basic residues Not Applicable

Polar residues Not Applicable

Molecular weight (Average) Not Applicable

Molecular weight (Monoisotopic) Not Applicable

Common amino acids Not Applicable

Net charge Not Applicable

Instability index (II) Not Applicable

Aliphatic index Not Applicable

Grand average of hydropathicity (GRAVY) Not Applicable

Half Life
Not Applicable

Extinction coefficients
Not Applicable

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID US2020/0157150A1

Patent Title Anticancer Peptides

Other Iinformation Patent Application; Family: 8s / 8ex; Family Jurisdictions: CA, CN, US, AU, JP, EP, WO, KR; Legal Status: Pending; Application No: 201816635902; Filed: Jul 31, 2018; Published: May 21, 2020; Earliest Priority: Aug 1, 2017

Other Published ID AU2018311129A1 CA3071601A1 CN111436200A EP3661947A1 JP2020529429A KR20200032730A WO2019025432A1