ANS-2

General Information


DCTPep ID  DCTPep01835

Peptide Name   ANS-2

Sequence  AVPSPPPAS

Sequence Length  9

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetics

Type  Synthetic peptide

Classification

  

ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  HaCaT, NHDF: Almost no toxicity to normal cells (fig. 8)

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C37H59N9O12

Absent amino acids  CDEFGHIKLMNQRTWY

Theoretical pI  5.57

Acidic residues  0

Basic residues  0

Polar residues  2

Molecular weight (Average)  821.93

Molecular weight (Monoisotopic)  821.43

Common amino acids  P

Net charge  0

Instability index (II)  164.71

Aliphatic index  54.44

Grand average of hydropathicity (GRAVY)  -0.022

Half Life 
  4.4 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID WO2021/025352A1

Patent Title  Anticancer Virus Expressing Fgf2- or Api5-Derived Peptide, and Use Thereof

Other Iinformation  Patent Application; Family: 3s / 3ex; Family Jurisdictions: WO, KR; Legal Status: Pending; Application No: 2020009856; Filed: Jul 27, 2020; Published: Feb 11, 2021; Earliest Priority: Aug 8, 2019

Other Published ID  KR102241134B1  KR20210017560A  




DCTPep is developed by Dr.Zheng's team.