Peptide Libraray

Varv He

General Information

DCTPep ID DCTPep01839

Peptide Name Varv He

Sequence GLPVCGETCFGGTCNTPGCSCXTWPVCSRN

Sequence Length 30

UniProt ID Not available

PubChem CID Not available

Origin Viola arvensis (European field pansy) (Field violet)

Type Native peptide

Classification

Membrane-targeted

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
BEL-7402	Human papillomavirus-related endocervical adenocarcinoma	IC50>10 µg/ml	SRB assay	48 h	1

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Cyclic

Disulfide/Other Bond Cys5<--->Cys19; Cys9<--->Cys21; Cys14<--->Cys27

N-terminal Modification Free

C-terminal Modification Free

Other Modification X=Glu-ethylation

Chiral L

Physicochemical Information

Formula Not Applicable

Absent amino acids Not Applicable

Theoretical pI Not Applicable

Acidic residues Not Applicable

Basic residues Not Applicable

Polar residues Not Applicable

Molecular weight (Average) Not Applicable

Molecular weight (Monoisotopic) Not Applicable

Common amino acids Not Applicable

Net charge Not Applicable

Instability index (II) Not Applicable

Aliphatic index Not Applicable

Grand average of hydropathicity (GRAVY) Not Applicable

Half Life
Not Applicable

Extinction coefficients
Not Applicable

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 20580652

Title Isolation and characterization of cytotoxic cyclotides from Viola tricolor

Doi 10.1016/j.peptides.2010.05.004

Year 2010

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available