Peptide Libraray

MIA-602

General Information

DCTPep ID DCTPep01847

Peptide Name MIA-602

Sequence YADAIFTNSYRKVLGQLSARKLLQDIMSR

Sequence Length 29

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

ACP Tumor active peptide Hormone stimulating peptides GHRH antagonists

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
HCT 15	Colon adenocarcinoma	~40%Inhibition=5 µM	MTT assay	70-72 h	1

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure DCTPep01847

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Phenylacetyl 12-aminododecanoyl

C-terminal Modification Amidation

Other Modification None

Chiral L

Physicochemical Information

Formula Not Applicable

Absent amino acids Not Applicable

Theoretical pI Not Applicable

Acidic residues Not Applicable

Basic residues Not Applicable

Polar residues Not Applicable

Molecular weight (Average) 3358.91

Molecular weight (Monoisotopic) 3356.8

Common amino acids Not Applicable

Net charge Not Applicable

Instability index (II) Not Applicable

Aliphatic index Not Applicable

Grand average of hydropathicity (GRAVY) Not Applicable

Half Life
Not Applicable

Extinction coefficients
Not Applicable

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 28130121

Title Synthesis and structure-activity studies on novel analogs of human growth hormone releasing hormone (GHRH) with enhanced inhibitory activities on tumor growth

Doi 10.1016/j.peptides.2017.01.009

Year 2017

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available