Peptide Libraray

LR(11)

General Information

DCTPep ID DCTPep01901

Peptide Name LR(11)

Sequence LRLRLRLRLRLRLRLRLRLRLR

Sequence Length 22

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

ACP Tumor active peptide

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
HeLa	Human papillomavirus-related endocervical adenocarcinoma	66.6% Killing=500µg/ml	MTS assay	24 h	Patent

Hemolytic Activity RBCs: 41%Hemolysis=250 µg/ml

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure DCTPep01901

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C132H255N55O23

Absent amino acids ACDEFGHIKMNPQSTVWY

Theoretical pI 13.00

Acidic residues 0

Basic residues 11

Polar residues 0

Molecular weight (Average) 2980.83

Molecular weight (Monoisotopic) 2979.05

Common amino acids LR

Net charge 11

Instability index (II) 105.85

Aliphatic index 195.00

Grand average of hydropathicity (GRAVY) -0.350

Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).

Extinction coefficients
Should not be visible by UV spectrophotometry.

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Not available

Doi Not available

Year Not available

Patent

Patent ID US7091185B2

Patent Title Periodic antimicrobial peptides

Other Iinformation Granted Patent; Family: 2s / 2ex; Family Jurisdictions: US; Legal Status: Inactive; Application No: 78521004; Filed: Feb 24, 2004; Published: Aug 15, 2006; Earliest Priority: Feb 24, 2003; Granted: Aug 15, 2006

Other Published ID US2005187151A1