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X13
General Information
DCTPep ID DCTPep01940
Peptide Name X13
Sequence MPFSTGKRIMLGE
Sequence Length 13
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
| Cell Line | Disease | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|
| MDA-MB-231 | Breast adenocarcinoma | Not active up to 100 µM | CellTox cytotoxicity assay | 30 min | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure DCTPep01940
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C64H107N17O18S2
Absent amino acids ACDHNQVWY
Theoretical pI 8.50
Acidic residues 1
Basic residues 2
Polar residues 4
Molecular weight (Average) 1466.78
Molecular weight (Monoisotopic) 1465.74
Common amino acids GM
Net charge 1
Instability index (II) 64.06
Aliphatic index 60.00
Grand average of hydropathicity (GRAVY) -0.069
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26734838
Title Use of a novel cytotoxic HEXIM1 peptide in the directed breast cancer therapy
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_12682
This work is licensed under a Creative Commons Attribution 4.0 International License.