This work is licensed under a Creative Commons Attribution 4.0 International License.
4
General Information
DCTPep ID DCTPep01948
Peptide Name 4
Sequence GLVMLVKKAGLT
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Membrane-targeted
Activity Information
| Cell Line | Disease | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|
| A549 | Lung adenocarcinoma | EC50>100 μM | MTT assay | 24 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C56H104N14O14S1
Absent amino acids CDEFHINPQRSWY
Theoretical pI 10.00
Acidic residues 0
Basic residues 2
Polar residues 3
Molecular weight (Average) 1229.59
Molecular weight (Monoisotopic) 1228.76
Common amino acids L
Net charge 2
Instability index (II) 6.77
Aliphatic index 154.17
Grand average of hydropathicity (GRAVY) 1.183
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30953170
Title De novo design of anticancer peptides by ensemble artificial neural networks
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_13112
This work is licensed under a Creative Commons Attribution 4.0 International License.