This work is licensed under a Creative Commons Attribution 4.0 International License.
B1CTcu5D
General Information
DCTPep ID DCTPep01980
Peptide Name B1CTcu5D
Sequence liaGlaanflpqilckiarkc
Sequence Length 21
UniProt ID E3SYG2 D2K8D1 C3RTH8
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Membrane-targeted
Activity Information
| Cell Line | Disease | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|
| A431 | Skin squamous cell carcinoma | 50% Cytotoxicity>100 µg/ml | MTT assay | Not available | 1 |
Hemolytic Activity Human erythrocytes: 40.22% Hemolysis=200 µg/ml
Normal (non-cancerous) Cytotoxicity HEK293: 50%Cytotoxicity>100 µg/ml; PBMC: 50%Cytotoxicity=71.4±2.3 µg/ml
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys15<--->Cys21
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral D
Physicochemical Information
Formula Not Applicable
Absent amino acids Not Applicable
Theoretical pI Not Applicable
Acidic residues Not Applicable
Basic residues Not Applicable
Polar residues Not Applicable
Molecular weight (Average) Not Applicable
Molecular weight (Monoisotopic) Not Applicable
Common amino acids Not Applicable
Net charge Not Applicable
Instability index (II) Not Applicable
Aliphatic index Not Applicable
Grand average of hydropathicity (GRAVY) Not Applicable
Half Life
Not Applicable
Extinction coefficients
Not Applicable
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25997127
Title Structure-Activity Relationship and Mode of Action of a Frog Secreted Antibacterial Peptide B1CTcu5 Using Synthetically and Modularly Modified or Deleted (SMMD) Peptides
Doi 10.1371/journal.pone.0124210
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPS_13667
This work is licensed under a Creative Commons Attribution 4.0 International License.