KA081020-065

General Information


DCTPep ID  DCTPep02003

Peptide Name   KA081020-065

Sequence  MRGENMSEGNRPEGTPHGLRSTPARELPIPAFLEPAR

Sequence Length  37

UniProt ID  I3TKW5 

PubChem CID  Not available

Origin  Tistrella mobilis (strain KA081020-065)

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  DCTPep02003

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C173H280N56O54S2

Absent amino acids  CDKQVWY

Theoretical pI  6.54

Acidic residues  5

Basic residues  6

Polar residues  10

Molecular weight (Average)  4072.59

Molecular weight (Monoisotopic)  4070.03

Common amino acids  P

Net charge  1

Instability index (II)  65.28

Aliphatic index  50.27

Grand average of hydropathicity (GRAVY)  -0.986

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 22458477

Title  Bacterial biosynthesis and maturation of the didemnin anti-cancer agents

Doi 10.1021/ja301735a

Year  2012

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DCTPep is developed by Dr.Zheng's team.