PTD-1, Protein transduction domain 1

General Information


DCTPep ID  DCTPep02349

Peptide Name   PTD-1, Protein transduction domain 1

Sequence  KRIIQRILSRNS

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Transducing peptide



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C63H118N24O17

Absent amino acids  ACDEFGHMPTVWY

Theoretical pI  12.30

Acidic residues  0

Basic residues  4

Polar residues  3

Molecular weight (Average)  1483.78

Molecular weight (Monoisotopic)  1482.91

Common amino acids  IR

Net charge  4

Instability index (II)  78.72

Aliphatic index  130.00

Grand average of hydropathicity (GRAVY)  -0.725

Half Life 
  1.3 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  3 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 11020349

Title  Characterization of a class of cationic peptides able to facilitate efficient protein transduction in vitro and in vivo

Doi 10.1006/mthe.2000.0137

Year  2000

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DCTPep is developed by Dr.Zheng's team.