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PTD-4, Protein transduction domain 4
General Information
DCTPep ID DCTPep02352
Peptide Name PTD-4, Protein transduction domain 4
Sequence PIRRRKKLRRLK
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Transducing peptide
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C71H138N30O13
Absent amino acids ACDEFGHMNQSTVWY
Theoretical pI 12.61
Acidic residues 0
Basic residues 8
Polar residues 0
Molecular weight (Average) 1620.07
Molecular weight (Monoisotopic) 1619.11
Common amino acids R
Net charge 8
Instability index (II) 154.27
Aliphatic index 97.50
Grand average of hydropathicity (GRAVY) -1.975
Half Life
>20 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
? (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 11020349
Title Characterization of a class of cationic peptides able to facilitate efficient protein transduction in vitro and in vivo
Year 2000
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.