PTD-6, Protein transduction domain 6
General Information
DCTPep ID DCTPep02354
Peptide Name PTD-6, Protein transduction domain 6
Sequence MHKRPTTPSRKM
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Transducing peptide
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C61H108N22O16S2
Absent amino acids ACDEFGILNQVWY
Theoretical pI 12.02
Acidic residues 0
Basic residues 5
Polar residues 3
Molecular weight (Average) 1469.79
Molecular weight (Monoisotopic) 1468.78
Common amino acids KMPRT
Net charge 5
Instability index (II) 179.12
Aliphatic index 0.00
Grand average of hydropathicity (GRAVY) -1.800
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 11020349
Title Characterization of a class of cationic peptides able to facilitate efficient protein transduction in vitro and in vivo
Year 2000
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available