DCTPep ID  DCTPep02401

Peptide Name   Temporin-1Sa [S3K] (3-13), SEQ ID NO:30 for Patent EP 2853538 A1

Sequence  KGIVGMLGKLE

Sequence Length  11

UniProt ID  B3KYH4 

PubChem CID  Not available

Origin  Synthetic (Derived from Temporin-1Sa)

Type  Synthetic peptide

Hemolytic Activity  Rat erythrocytes: LC50=618 µM

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L

Grand average of hydropathicity (GRAVY)  0.518

Half Life 
  1.3 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  3 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution

Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID EP 2853538 A1

Patent Title  Analogues of temporin-SHa and uses thereof

Other Iinformation  Patent Application; Family: 11s / 11ex; Family Jurisdictions: CA, EP, JP, BR, US, WO, ES; Legal Status: Discontinued; Application No: 13306344; Filed: Sep 27, 2013; Published: Apr 1, 2015; Earliest Priority: Sep 27, 2013

Other Published ID  BR112016006424A2  CA2924035A1  EP3049432A1  EP3049432B1  ES2691323T3  JP2016539658A  JP6669656B2  US2016280749A1  US9932376B2  WO2015044356A1