Peptide Libraray

CLB-CREKA

General Information

DCTPep ID DCTPep02530

Peptide Name CLB-CREKA

Sequence CREKA

Sequence Length 5

UniProt ID Not available

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

Coupling peptide

Activity Information

Cell Line	Disease	Activity	Assay	Testing Time	Literature
CAPAN-1	Pancreatic ductal adenocarcinoma	IC50>200 µM	MTT assay	48 h	1
MCF-7	Invasive breast carcinoma of no special type	IC50>200 µM	MTT assay	48 h	1

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity NIH 3T3: IC50>200 µM

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Chlorambucil

C-terminal Modification Amidation

Other Modification None

Chiral L

Physicochemical Information

Formula Not Applicable

Absent amino acids Not Applicable

Theoretical pI Not Applicable

Acidic residues Not Applicable

Basic residues Not Applicable

Polar residues Not Applicable

Molecular weight (Average) Not Applicable

Molecular weight (Monoisotopic) Not Applicable

Common amino acids Not Applicable

Net charge Not Applicable

Instability index (II) Not Applicable

Aliphatic index Not Applicable

Grand average of hydropathicity (GRAVY) Not Applicable

Half Life
Not Applicable

Extinction coefficients
Not Applicable

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 24480922

Title Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties

Doi 10.1039/c3ob42422g

Year 2014

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available