This work is licensed under a Creative Commons Attribution 4.0 International License.
Desotamide F
General Information
DCTPep ID DCTPep02600
Peptide Name Desotamide F
Sequence WLxXNG
Sequence Length 6
UniProt ID Not available
PubChem CID 139588177
Origin Streptomyces nov. sp.
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
| Cell Line | Disease | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|
| NCI-H460 | Lung large cell carcinoma | Not active up to 30 µM | MTT assay | 68 h | 1 |
| SW620 | Colon adenocarcinoma | Not active up to 30 µM | MTT assay | 68 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: Trp1<--->Gly6
N-terminal Modification Free
C-terminal Modification Free
Other Modification x=D-Allo-Ile; X=Allo-Ile
Chiral Mix
Physicochemical Information
Formula Not Applicable
Absent amino acids Not Applicable
Theoretical pI Not Applicable
Acidic residues Not Applicable
Basic residues Not Applicable
Polar residues Not Applicable
Molecular weight (Average) Not Applicable
Molecular weight (Monoisotopic) Not Applicable
Common amino acids Not Applicable
Net charge Not Applicable
Instability index (II) Not Applicable
Aliphatic index Not Applicable
Grand average of hydropathicity (GRAVY) Not Applicable
Half Life
Not Applicable
Extinction coefficients
Not Applicable
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25229313
Title Wollamides: antimycobacterial cyclic hexapeptides from an Australian soil Streptomyces
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPN_7160
This work is licensed under a Creative Commons Attribution 4.0 International License.